PIP5K1A

Phosphatidylinositol-4-phosphate 5-kinase type-1 alpha is an enzyme that in humans is encoded by the PIP5K1A gene.^[5][6][7]

AliasesPIP5K1A, phosphatidylinositol-4-phosphate 5-kinase type 1 alpha

External IDsOMIM: 603275; MGI: 107929; HomoloGene: 93492; GeneCards: PIP5K1A; OMA:PIP5K1A - orthologs

Chr.Chromosome 1 (human)^[1]

End151,249,536 bp^[1]

Quick facts Identifiers, Aliases ...

PIP5K1A
Identifiers
Aliases	PIP5K1A, phosphatidylinositol-4-phosphate 5-kinase type 1 alpha
External IDs	OMIM: 603275; MGI: 107929; HomoloGene: 93492; GeneCards: PIP5K1A; OMA:PIP5K1A - orthologs
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q21.3 Start 151,197,949 bp[1] End 151,249,536 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.1 Start 95,058,530 bp[2] End 95,106,930 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right testis epithelium of colon left testis sural nerve Achilles tendon gastric mucosa skin of leg left uterine tube skin of abdomen islet of Langerhans Top expressed in gastrula Rostral migratory stream decidua olfactory tubercle cumulus cell CA3 field dentate gyrus pineal gland dentate gyrus of hippocampal formation granule cell primary motor cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding 1-phosphatidylinositol-4-phosphate 5-kinase activity kinase activity kinase binding protein binding phosphatidylinositol phosphate kinase activity ATP binding 1-phosphatidylinositol-3-phosphate 5-kinase activity 1-phosphatidylinositol-5-kinase activity phosphatidylinositol-3,4-bisphosphate 5-kinase activity 1-phosphatidylinositol-3-phosphate 4-kinase activity Cellular component nuclear speck mRNA cleavage and polyadenylation specificity factor complex cell projection membrane focal adhesion ruffle plasma membrane nucleoplasm ruffle membrane nucleus lamellipodium cytoplasm cytosol Biological process fibroblast migration actin cytoskeleton reorganization phosphatidylinositol metabolic process activation of GTPase activity phosphorylation keratinocyte differentiation focal adhesion assembly phospholipid biosynthetic process phagocytosis cell chemotaxis glycerophospholipid metabolic process ruffle assembly cell migration signal transduction phosphatidylinositol phosphate biosynthetic process regulation of phosphatidylinositol 3-kinase signaling phosphatidylinositol biosynthetic process protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8394 18720 Ensembl ENSG00000143398 ENSMUSG00000028126 UniProt Q99755 P70182 RefSeq (mRNA) NM_001135636 NM_001135637 NM_001135638 NM_003557 NM_001330689 NM_001293707 NM_008847 RefSeq (protein) NP_001129108 NP_001129109 NP_001129110 NP_001317618 NP_003548 NP_001280636 NP_032873 Location (UCSC) Chr 1: 151.2 – 151.25 Mb Chr 3: 95.06 – 95.11 Mb PubMed search [3] [4]
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