PLAGL1

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

Zinc finger protein PLAGL1 is a protein that in humans is encoded by the PLAGL1 gene.[5][6][7]

AliasesPLAGL1, LOT1, ZAC, ZAC1, PLAG1 like zinc finger 1
End144,064,599 bp[1]
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PLAGL1
Identifiers
AliasesPLAGL1, LOT1, ZAC, ZAC1, PLAG1 like zinc finger 1
External IDsOMIM: 603044; MGI: 1100874; HomoloGene: 31401; GeneCards: PLAGL1; OMA:PLAGL1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_009538

RefSeq (protein)

n/a

Location (UCSC)Chr 6: 143.94 – 144.06 MbChr 10: 13.06 – 13.13 Mb
PubMed search[3][4]
Wikidata
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Function

This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate. Many transcript variants encoding two different isoforms have been found for this gene.[7]

Interactions

PLAGL1 has been shown to interact with P53.[8]

References

Further reading

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