PLCD4

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4 is an enzyme that in humans is encoded by the PLCD4 gene.^[5][6][7]

AliasesPLCD4, phospholipase C delta 4

External IDsOMIM: 605939; MGI: 107469; HomoloGene: 88782; GeneCards: PLCD4; OMA:PLCD4 - orthologs

Chr.Chromosome 2 (human)^[1]

End218,637,184 bp^[1]

Quick facts Identifiers, Aliases ...

PLCD4
Identifiers
Aliases	PLCD4, phospholipase C delta 4
External IDs	OMIM: 605939; MGI: 107469; HomoloGene: 88782; GeneCards: PLCD4; OMA:PLCD4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q35 Start 218,607,855 bp[1] End 218,637,184 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 C4|1 38.54 cM Start 74,582,047 bp[2] End 74,606,953 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh vastus lateralis muscle gastrocnemius muscle skeletal muscle tissue Skeletal muscle tissue of rectus abdominis biceps brachii deltoid muscle Skeletal muscle tissue of biceps brachii tibialis anterior muscle gastric mucosa Top expressed in medial head of gastrocnemius muscle triceps brachii muscle knee joint vastus lateralis muscle seminiferous tubule spermatid sternocleidomastoid muscle spermatocyte tibialis anterior muscle skeletal muscle tissue More reference expression data BioGPS More reference expression data
Gene ontology Molecular function phosphoric diester hydrolase activity phospholipase C activity calcium ion binding hydrolase activity signal transducer activity metal ion binding phosphatidylinositol phospholipase C activity Cellular component plasma membrane nuclear membrane intracellular anatomical structure endoplasmic reticulum nucleus membrane cytoplasm endoplasmic reticulum membrane cytosol Biological process lipid catabolic process acrosome reaction intracellular signal transduction phosphatidylinositol metabolic process signal transduction lipid metabolism inositol phosphate metabolic process inositol trisphosphate biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84812 18802 Ensembl ENSG00000115556 ENSMUSG00000026173 UniProt Q9BRC7 Q8K3R3 RefSeq (mRNA) NM_032726 NM_001081456 NM_148937 RefSeq (protein) NP_116115 NP_001074925 NP_683739 Location (UCSC) Chr 2: 218.61 – 218.64 Mb Chr 1: 74.58 – 74.61 Mb PubMed search [3] [4]
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