PLSCR4

Phospholipid scramblase 4, also known as Ca²⁺-dependent phospholipid scramblase 4, is a protein that is encoded in humans by the PLSCR4 gene.^[5][6]

AliasesPLSCR4, TRA1, phospholipid scramblase 4

External IDsOMIM: 607612; MGI: 2143267; GeneCards: PLSCR4

PDBOrtholog search: PDBe RCSB

Chr.Chromosome 3 (human)^[1]

Quick facts Identifiers, Aliases ...

PLSCR4
Identifiers
Aliases	PLSCR4, TRA1, phospholipid scramblase 4
External IDs	OMIM: 607612; MGI: 2143267; GeneCards: PLSCR4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3Q5U
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q24 Start 146,192,335 bp[1] End 146,251,179 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 E3.3 Start 92,339,426 bp[2] End 92,374,509 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium parietal pleura Achilles tendon tibial nerve pericardium visceral pleura ascending aorta Descending thoracic aorta synovial joint optic nerve Top expressed in sciatic nerve iris lumbar spinal ganglion carotid body lung right kidney left lung lobe right lung esophagus ciliary body More reference expression data BioGPS n/a
Gene ontology Molecular function SH3 domain binding phospholipid scramblase activity enzyme binding calcium ion binding CD4 receptor binding protein binding Cellular component integral component of membrane plasma membrane membrane Biological process cellular response to lipopolysaccharide plasma membrane phospholipid scrambling Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 57088 235527 Ensembl ENSG00000114698 ENSMUSG00000032377 UniProt Q9NRQ2 P58196 RefSeq (mRNA) NM_001128304 NM_001128305 NM_001128306 NM_001177304 NM_020353 NM_178711 RefSeq (protein) NP_001121776 NP_001121777 NP_001121778 NP_001170775 NP_065086 NP_848826 Location (UCSC) Chr 3: 146.19 – 146.25 Mb Chr 9: 92.34 – 92.37 Mb PubMed search [3] [4]
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