POLR3B

POLR3B
Identifiers
Aliases	POLR3B, C128, HLD8, INMAP, RPC2, polymerase (RNA) III subunit B, RNA polymerase III subunit B, CMT1I
External IDs	OMIM: 614366; MGI: 1917678; HomoloGene: 6981; GeneCards: POLR3B; OMA:POLR3B - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	106,510,198 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	84,563,042 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; endothelial cell; ; gingival epithelium; ; amniotic fluid; ; hair follicle; ; kidney tubule; ; germinal epithelium; ; Epithelium of choroid plexus; ; tibialis anterior muscle; ; gonad;
	Top expressed in
	tail of embryo; ; genital tubercle; ; lumbar spinal ganglion; ; epiblast; ; hand; ; submandibular gland; ; granulocyte; ; secondary oocyte; ; primitive streak; ; zygote;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; DNA binding; nucleotidyltransferase activity; ribonucleoside binding; metal ion binding; RNA polymerase III activity; DNA-directed 5'-3' RNA polymerase activity;
Cellular component	cytosol; nucleoplasm; RNA polymerase III complex; nucleus;
Biological process	immune system process; transcription, DNA-templated; defense response to virus; positive regulation of innate immune response; positive regulation of interferon-beta production; innate immune response; transcription by RNA polymerase III; positive regulation of type I interferon production;
	Sources:Amigo / QuickGO
Orthologs
	55703
	70428
	ENSG00000013503
	ENSMUSG00000034453
	Q9NW08
	P59470
	NM_018082; NM_001160708
	NM_027423
	NP_001154180; NP_060552
	NP_081699
	Wikidata
View/Edit Human	View/Edit Mouse

AliasesPOLR3B, C128, HLD8, INMAP, RPC2, polymerase (RNA) III subunit B, RNA polymerase III subunit B, CMT1I

External IDsOMIM: 614366; MGI: 1917678; HomoloGene: 6981; GeneCards: POLR3B; OMA:POLR3B - orthologs

Chr.Chromosome 12 (human)^[1]

End106,510,198 bp^[1]

RNA polymerase III subunit B is an enzyme which is encoded by the gene POLR3B is a gene that in humans encodes the second largest subunit of RNA polymerase III.^[5]

[1]

[2]

[3]

[4]

[5]

POLR3B

Function

Clinical significance

References

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