PORCN

From Wikipedia, the free encyclopedia

AliasesPORCN, DHOF, FODH, MG61, PORC, PPN, porcupine homolog (Drosophila), porcupine O-acyltransferase
End48,520,814 bp[1]
PORCN
Identifiers
AliasesPORCN, DHOF, FODH, MG61, PORC, PPN, porcupine homolog (Drosophila), porcupine O-acyltransferase
External IDsOMIM: 300651; MGI: 1890212; HomoloGene: 41529; GeneCards: PORCN; OMA:PORCN - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016913
NM_023638
NM_145907
NM_145908
NM_001308474

RefSeq (protein)

NP_001269096
NP_073736
NP_982299
NP_982300
NP_982301

NP_001295403
NP_058609
NP_076127
NP_665914
NP_665915

Location (UCSC)Chr X: 48.51 – 48.52 MbChr X: 8.06 – 8.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

PORCN (porcupine homolog – Drosophila) is a human gene.[5][6] The protein is homologous to other membrane-bound O-acyltransferases.

The protein encoded by this gene is an endoplasmic reticulum transmembrane protein involved in processing of wingless proteins such as WNT7A. It performs O-Palmitoleoylation of these proteins.[6]

Clinical significance

Ligands

References

Related Articles

Wikiwand AI