PPIP5K2
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
Diphosphoinositol pentakisphosphate kinase 2 is a protein that in humans is encoded by the PPIP5K2 gene. [5]
AliasesPPIP5K2, HISPPD1, IP7K2, VIP2, CFAP160, diphosphoinositol pentakisphosphate kinase 2, DFNB100
External IDsOMIM: 611648; MGI: 2142810; HomoloGene: 49409; GeneCards: PPIP5K2; OMA:PPIP5K2 - orthologs
Function
Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell signaling molecules.
HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24) activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et al., 2007 [PubMed 17690096]).