PPP3R1

PPP3R1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1AUI, 1M63, 1MF8, 2P6B, 3LL8, 4F0Z, 4OR9, 4ORA, 4ORC, 4ORB
Identifiers
Aliases	PPP3R1, CALNB1, CNB, CNB1, protein phosphatase 3 regulatory subunit B, alpha
External IDs	OMIM: 601302; MGI: 107172; HomoloGene: 68099; GeneCards: PPP3R1; OMA:PPP3R1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	68,256,237 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	17,150,375 bp
RNA expression pattern
	Top expressed in
	Brodmann area 9; ; nucleus accumbens; ; Achilles tendon; ; right frontal lobe; ; monocyte; ; caudate nucleus; ; prefrontal cortex; ; putamen; ; cerebellar hemisphere; ; amygdala;
	Top expressed in
	CA3 field; ; perirhinal cortex; ; Region I of hippocampus proper; ; olfactory tubercle; ; entorhinal cortex; ; dentate gyrus; ; prefrontal cortex; ; primary motor cortex; ; primary visual cortex; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; protein domain specific binding; metal ion binding; calmodulin binding; protein binding; calcium-dependent protein serine/threonine phosphatase activity; cyclosporin A binding; phosphoprotein phosphatase activity; phosphatase binding;
Cellular component	cytoplasm; cytosol; membrane; plasma membrane; nucleoplasm; sarcolemma; calcineurin complex; mitochondrion;
Biological process	Fc-epsilon receptor signaling pathway; positive regulation of transcription by RNA polymerase II; protein dephosphorylation; Wnt signaling pathway, calcium modulating pathway; branching involved in blood vessel morphogenesis; epithelial to mesenchymal transition; development of the heart; Schwann cell development; myelination in peripheral nervous system; calcineurin-NFAT signaling cascade; protein localization to nucleus; lung epithelial cell differentiation; protein import into nucleus; positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	5534
	19058
	ENSG00000221823
	ENSMUSG00000033953
	P63098
	Q63810
	NM_000945
	NM_024459
	NP_000936
	NP_077779
	Wikidata
View/Edit Human	View/Edit Mouse

Calcineurin subunit B type 1 also known as protein phosphatase 2B regulatory subunit 1 is a protein that in humans is encoded by the PPP3R1 gene.^[5]^[6]^[7]