PRICKLE1

PRICKLE1
Identifiers
Aliases	PRICKLE1, EPM1B, RILP, prickle planar cell polarity protein 1
External IDs	OMIM: 608500; MGI: 1916034; HomoloGene: 17686; GeneCards: PRICKLE1; OMA:PRICKLE1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	42,590,355 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	93,493,772 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; tendon of biceps brachii; ; lateral nuclear group of thalamus; ; spinal ganglia; ; endothelial cell; ; trigeminal ganglion; ; myocardium of left ventricle; ; parietal pleura; ; internal globus pallidus; ; cardiac muscle tissue of right atrium;
	Top expressed in
	digit; ; phalanx of foot; ; zygote; ; secondary oocyte; ; phalanx of second toe; ; phalanx of fourth toe; ; middle finger; ; primary oocyte; ; phalanx of big toe; ; phalanx of middle finger;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding; metal ion binding; protein binding;
Cellular component	nuclear membrane; nucleus; membrane; cytoplasm; cytosol;
Biological process	negative regulation of canonical Wnt signaling pathway; positive regulation of protein ubiquitination; coronary vasculature development; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; neural tube closure; aorta development; negative regulation of cardiac muscle cell myoblast differentiation; negative regulation of transcription, DNA-templated; Wnt signaling pathway, planar cell polarity pathway; protein import into nucleus;
	Sources:Amigo / QuickGO
Orthologs
	144165
	106042
	ENSG00000139174
	ENSMUSG00000036158
	Q96MT3
	Q3U5C7
	NM_001144881; NM_001144882; NM_001144883; NM_153026
	NM_001033217; NM_001364846
	NP_001138353; NP_001138354; NP_001138355; NP_694571
	NP_001028389; NP_001351775
	Wikidata
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