Since every paired dominating set is a dominating set, and every dominating set whose induced subgraph has a perfect matching is necessarily a total dominating set, the following chain of inequalities holds for any graph
without isolated vertices:[1]

where
is the domination number and
is the total domination number.
Haynes and Slater characterized the triples
of positive integers with
for which there exists a graph
satisfying
,
, and
.[1]
Because the endpoints of any maximal matching form a paired dominating set, the paired domination number is bounded above by twice the size of any maximal matching of the graph:[2]

where
denotes the size of a maximum matching.
Define the family
as the set of graphs obtainable from three nonempty sets of parallel edges,
,
, and
, by connecting each pair of vertices
,
, and
with a path of length two (introducing a new vertex of degree two for each such pair). The original
edges are called the associated matching of the resulting graph. When
, the resulting graph is the cycle graph
.
A connected, leafless graph of girth at least seven has a maximal matching whose endpoints form a minimum paired dominating set if and only if it belongs to the family
.[2]
A consequence of this characterization is that any such graph containing an 8-cycle must contain a specific 18-vertex graph, denoted
, as an induced subgraph; this occurs precisely when at least two of the parameters
are at least 2.[2]