The main economic activities in Patayamatebele are farming and gathering wild berries.
The cattle in the area were destroyed due to foot-and-mouth disease in the 2002/2003 period.
In September 2012, Peter Siele, the Minister of Local Government, said Patayamatebele and nearby Matopi would be recommended for the Remote Area Service Allowance due to their distance from banks and shops and lack of public transport. Roads to the village are in poor condition. The village has a primary school. Medical services are provided by a mobile clinic.
The village does not have telephone service.
Before construction of the Dikgatlhong Dam began, in 2008 the government arranged for counselling services on AIDS to residents of the Mmadinare, Robelela, Matopi, Matsiloje, Chokwe and Patayamatebele villages.
Preparations were made for additional demands for health and policing services.