Peptitergents
From Wikipedia, the free encyclopedia
Peptitergents (a portmanteau of peptide and detergent) are synthetic peptides designed to be lipophilic on one side and hydrophilic on the other upon folding to an α-helical conformation and were designed to solubilize integral membrane proteins in aqueous solution.[1] They can be considered a sub-class of amphipols and are based on earlier fundamental explorations of amphiphilic secondary structures[2]
