Pheneturide

Pheneturide
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	N03AX13 (WHO) ;
Identifiers
	IUPAC name (RS)-N-Carbamoyl-2-phenyl-butanamide;
CAS Number	90-49-3 ;
PubChem CID	72060;
ChemSpider	65046 ;
UNII	878CEJ4HGX;
KEGG	D01190 ;
CompTox Dashboard (EPA)	DTXSID4020612 ;
ECHA InfoCard	100.001.817
Chemical and physical data
Formula	C11H14N2O2
Molar mass	206.245 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES O=C(N)NC(=O)C(c1ccccc1)CC;
	InChI InChI=1S/C11H14N2O2/c1-2-9(10(14)13-11(12)15)8-6-4-3-5-7-8/h3-7,9H,2H2,1H3,(H3,12,13,14,15) ; Key:AJOQSQHYDOFIOX-UHFFFAOYSA-N ;
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Pheneturide (INN, BAN) (brand names Benuride, Deturid, Pheneturid, Septotence, Trinuride),^[1] also known as phenylethylacetylurea (or ethylphenacemide), is an anticonvulsant of the ureide class.^[2]^[3] Conceptually, it can be formed in the body as a metabolic degradation product from phenobarbital. It is considered to be obsolete^[4] and is now seldom used.^[5] It is marketed in Europe, including in Poland, Spain and the United Kingdom.^[6] Pheneturide has a similar profile of anticonvulsant activity and toxicity relative to phenacemide.^[7]^[8] As such, it is only used in cases of severe epilepsy when other, less-toxic drugs have failed.^[8] Pheneturide inhibits the metabolism and thus increases the levels of other anticonvulsants, such as phenytoin.^[5]^[6]