Phosphonoacetaldehyde reductase (NADH)

Enzyme From Wikipedia, the free encyclopedia

Phosphonoacetaldehyde reductase (NADH) (EC 1.1.1.309, PhpC) is an enzyme with systematic name 2-hydroxyethylphosphonate:NAD+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction

2D representation of the chemical structure of Q27105414.
2-hydroxyethylphosphonic acid
 
 
 
H+
Reversible left-right reaction arrow with minor forward product(s) to top right and minor reverse substrate(s) from bottom right
 
H+
 
2D representation of the chemical structure of Q27094110.
phosphonoacetaldehyde
 

The enzyme from Streptomyces viridochromogenes catalyses a step in the biosynthesis of phosphinothricin tripeptide, the reduction of phosphonoacetaldehyde to 2-hydroxyethylphosphonic acid.[2]

References

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