Phrenitis
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The term phrenitis was employed in ancient Greece by Hippocrates and his followers. It refers to acute inflammation of mind and body, not in a theoretical but in a descriptive sense. Its presumed seat was never anatomically or conceptually well determined. The diagnosis was used during the Middle Ages: a mental confusion or continuous delirium with fever.
Phrenitis means an inflammation of the brain, or of the meninges of the brain, attended with acute fever and delirium. Symptoms vary widely in severity, from short-lived, relatively slight effects of headache, drowsiness, and fever to paralysis, coma, and death.