+ 4 reduced
ferredoxin
Phycocyanobilin:ferredoxin oxidoreductase
From Wikipedia, the free encyclopedia
In enzymology, phycocyanobilin:ferredoxin oxidoreductase (PcyA, EC 1.3.7.5) is an enzyme that catalyzes the chemical reaction
-phycocyanobilin.svg)
| phycocyanobilin:ferredoxin oxidoreductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.7.5 | ||||||||
| CAS no. | 347401-12-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The two substrates of this enzyme are biliverdin and reduced ferredoxin. Its products are (2R,3Z)-phycocyanobilin and oxidized ferredoxin.[1][2][3][4]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is (3Z)-phycocyanobilin:ferredoxin oxidoreductase. This enzyme participates in the catabolism of heme.[2]
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2D1E, 2DKE, and 2G18.
