Phycoerythrobilin synthase

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Phycoerythrobilin synthase (EC 1.3.7.6, PebS) is an enzyme with systematic name (3Z)-phycoerythrobilin:ferredoxin oxidoreductase (from biliverdin IX alpha).[1][2] It catalyses the following chemical reaction

+ 2 reduced
ferredoxin
 
 
 
 
Reversible left-right reaction arrow
 
 
 
+ 2 oxidised
ferredoxin
 

This enzyme, from a cyanophage infecting oceanic cyanobacteria of the Prochlorococcus genus carries out in one step the reduction of biliverdin to (3Z)-phycoerythrobilin. The same overall reaction results from the action of 15,16-dihydrobiliverdin:ferredoxin oxidoreductase and phycoerythrobilin:ferredoxin oxidoreductase in oxygenic organisms.[3][4]

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