Phyllis Rountree

Rountree was born in 1911 in Hamilton, Victoria. Her mother's brother, William Roy Hodgson was a noted diplomat, but she was inspired by her learned aunts. She went to school locally at Hamilton and Alexandra College before boarding in Hawthorn at the Tintern Church of England Girls’ Grammar School.^[1] She studied zoology and bacteriology at the University of Melbourne. She had hoped to study medicine like her aunt but her father, a pharmacist, said she was "too young".^[1] It was a chance visit to her home town by Harold Addison Woodruff that inspired Rountree and persuaded her father that she should pursue a master's degree and become a bacteriologist.^[2]

She completed three years of a Council of Scientific & Industrial Research fellowship in 1934 by presenting her work to Professor James A. Prescott at the Waite Agricultural Research Institute in Adelaide. He made no additions or changes but she was not offered a permanent position, which she attributed to systemic gender bias. She had enjoyed the relaxed attitude there but male colleagues had not spoken to her during her work breaks and she was sure that a man successfully completing three years of research would have been retained.^[2] “‘Well now, it was very nice having you here dear, but we don't employ women permanently’” is how Rountree recalled her fellowship. She reflected on not being offered a continuing position at the institute, noting later in her life that “‘if I'd been a man, they probably would have found me something’”.^[3][4]

In 1936 she went to London where she studied for a post-graduate Diploma in Bacteriology at the London School of Hygiene. She supported herself by working at the British Public Health Laboratory and she returned to Australia the following year.^[5]

After a year of food testing during the war,^[5] she started at the Royal Prince Alfred Hospital in 1944^[5] where she was suspected of recruiting communists. The commonwealth authorities decided she was not interested in this in the 1950s. At this time she was a recognised expert on staphylococcal infections^[1] and she had noticed a growth in the number of surgical infections. There was a concern that this might have meant a return to pre-penicillin type infections.^[7] This was not the case and she become the chief bacteriologist in 1961.

In 1954, a profoundly virulent strain of staphylococcus called “80/81” surfaced in Australia and soon after in Canada. The strain appeared initially during a study of infections in the nursery at Royal North Shore Hospital in Sydney, Australia. In the nursery, five infants were found to have staphylococcal lesions that were unresponsive to penicillin. The chief researchers who found this infection called on Rountree, who had been using the emerging technique of phage typing, to identify the strain of staphylococcus infecting the babies using phage typing. Rountree found that the strain could only be typed using chemically modified bacteriophages, leading the researchers to believe that it was a novel strain. Rountree was responsible for the study of all staphylococcal infections at RNS Hospital, and uncovered that almost 50% of strains present were of the new type before it vanished and was replaced by a new strain in June 1953 that was similarly untypable. Rountree worked with members of the Staphylococcal Reference Laboratory in London, England, particularly Dr. Robert E. O. Williams, who confirmed that the RNS strain she sent could not be typed by any of the bacteriophages in Williams’ laboratory. The phage was termed “80”; studies from March 1953 to March 1954 uncovered a new staphylococcus strain was detected in Canada at an Ottawa hospital that demonstrated an inability to be typed, named by its investigators “81”. Rountree’s 80 strain was ultimately found to be identical to the Canadian 81 strain found by Dr. E. T. Bynoe, Dr. R. H. Elder, and Dr. R. D. Comtois. In 1955, Rountree reported that staphylococcus strain 80/81 was the culprit of 19 of every 23 cases of staphylococcus infection in Australian neonates and that the strain was carried by babies into the general community, countering an initial finding that the strain was restricted to hospital-contracted infections. Strain 80/81 eventually came to be found in Australia, New Zealand, Canada, Great Britain, and across the United States. The infectious strain devastated hospitals and confounded providers and bacteriologists with symptoms that included severe skin lesions in infants, abscesses in mothers’ breasts, and nurses with severe boils. The 1950 epidemics in nurseries gave bacteriologists like Rountree and others an opportunity to revitalize infection control procedures in the absence of an effective antibiotic to treat the 80/81 strain.^[8][9] In 1956, Rountree and other medical and scientific professionals co-authored the first manual pertaining to the management of hospital nursery staphylococcal infection.^[10] While the 80/81 strain’s prevalence faded in the 1960s, Rountree referenced this work she engaged in as the most important work of her career.^[11][1] In 1971 she was appointed Honorary Research Associate in Medical Microbiology at the University of New South Wales.^[5]