Phytoene synthase
Class of enzymes
From Wikipedia, the free encyclopedia
Phytoene synthase (EC 2.5.1.32, prephytoene-diphosphate synthase, 15-cis-phytoene synthase, PSase, geranylgeranyl-diphosphate geranylgeranyltransferase) is a transferase enzyme involved in the biosynthesis of carotenoids. It catalyzes the conversion of geranylgeranyl pyrophosphate to phytoene.[1][2][3][4] This enzyme catalyses the following chemical reaction
- 2 geranylgeranyl diphosphate 15-cis-phytoene + 2 diphosphate (overall reaction)
- (1a) 2 geranylgeranyl diphosphate diphosphate + prephytoene diphosphate
- (1b) prephytoene diphosphate 15-cis-phytoene + diphosphate
| 15-cis-phytoene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.5.1.32 | ||||||||
| CAS no. | 50936-61-3 | ||||||||
| Databases | |||||||||
| BRENDA | enzyme data | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | enzyme entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| Rhea | reactions | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme requires Mn2+ for activity. It belongs to squalene/phytoene synthase family of proteins.
