Guitton studied at the École supérieure des beaux-arts de Tours [fr], where he earned a degree in painting in 1962.[2] In 1969, he began his career at Charlie Mensuel.[2] In 1971, he founded the magazine Zinc alongside Nicoulaud [fr], where they published underground comic strip reviews. The magazine folded in 1974.[2]
From 1975 to 1987, Guitton published his designs and comic strips in Charlie Mensuel Hara-Kiri, À Suivre, and Zero.[2] In 1987, he ceased collaboration with all magazines and devoted himself to painting. He became a well-known painter throughout Indre-et-Loir, participating in multiple artistic exhibitions and cultural manifestations.[1]
In 2011, a retrospective titled Pierre Guitton rétrospective : Et c'est pas fini ! was published. It highlighted his designs published in Charlie Mensuel and Zinc. In 2018, another retrospective titled Contes du Lapin jaune covered his publications in À Suivre from 1985 to 1987.[3]
Pierre Guitton died on 20 July 2021 at the age of 77.[4]