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Pierre Tiollais

French medical doctor (1934–2024) From Wikipedia, the free encyclopedia

Pierre Jean René Noël Tiollais (8 December 1934 – 5 August 2024) was a French medical doctor and biologist.

Life and career

Tiollais was born in Rennes on 8 December 1934. He was a member of the French Academy of sciences[1] of the Institute Pasteur and the French Academy of Medicine.[2]

In 1979, in collaboration with Francis Galibert, he carried out the complete sequencing of the hepatitis B virus genome, which made it possible to manufacture the first detection tests and screening for this disease.[citation needed]

In 1985, with his collaborators at the Institute Pasteur, he created a vaccine obtained by genetic engineering (recombinant vaccine) against hepatitis B, prepared on Chinese hamster ovary cells (CHO) .[3] His team were the first to create the hepatitis B vaccine using CHO cells. In 1990, he received the research prize from the Allianz-Institut de France Foundation.[4]

Tiollais died on 5 August 2024, at the age of 89.[5]

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