Pipofezine
Chemical compound
From Wikipedia, the free encyclopedia
Pipofezine, sold under the brand name Azafen or Azaphen, is a tricyclic antidepressant approved in Russia for the treatment of depression.[1][2][3][4] It was introduced in the late 1960s and is still used today.[5][6]
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| Trade names | Azafen, Azaphen |
| Routes of administration | Oral |
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| Formula | C16H19N5O |
| Molar mass | 297.362 g·mol−1 |
Pipofezine has been shown to act as a potent inhibitor of the reuptake of serotonin.[7][8] In addition to its antidepressant action, pipofezine has sedative effects as well, suggesting antihistamine activity.[9] Other properties such as anticholinergic or antiadrenergic actions are less clear but are likely.[citation needed]
