In Issue 23 of Imagine, Mike Dean pointed out that because of the adventure's complexity and the necessity of adapting it to a role-playing system, it "will provide your group with many sessions of play, but only if you are prepared to put in the necessary time and work for conversion and full understanding of the plots running through each of them."[1]
In the September 1983 edition of Dragon (#77), Roger E. Moore was not a fan, stating that "Plague of Terror is plagued by some terrible problems." He found the number of plots and sub-plot excessive, and too tightly interwoven for inexperienced gamemasters to easily sort through. He also found the use of "torture, child abuse, sexual assault, sadistic vengeance, and other such activities" to be gratuitous. He concluded with a recommendation to give this a miss, saying, "I cannot recommend this module for inexperienced role-players, for referees who like to do their own creative thinking in role-playing NPCs and setting up scenarios, or for those who feel uncomfortable with violence, torture, etc., etc."[3]