Peginterferon beta-1a

Medication From Wikipedia, the free encyclopedia

Peginterferon beta-1a, sold under the brand name Plegridy, is medication used to treat multiple sclerosis.[4][5]

Trade namesPlegridy, Plegridy Pen
Other namesBIIB-017
Quick facts Clinical data, Trade names ...
Peginterferon beta-1a
Clinical data
Trade namesPlegridy, Plegridy Pen
Other namesBIIB-017
AHFS/Drugs.comMonograph
MedlinePlusa614059
License data
Pregnancy
category
Routes of
administration
Subcutaneous injection
Drug classAntineoplastic agent
ATC code
Legal status
Legal status
Identifiers
  • 1-Ether with N-(3-hydroxy-2-methylpropyl)interferon β-1a (human) α-methyl-ω-hydroxy-poly(oxy-1,2-ethanediyl)
CAS Number
DrugBank
UNII
KEGG
Chemical and physical data
FormulaC913H1417N246O256PS7 [C2H4O]n
Molar mass44000 g·mol−1
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The most common side effects include headache, muscle pain, joint pain, influenza (flu)-like symptoms, pyrexia (fever), chills, asthenia (weakness), and erythema (reddening of the skin), pain or pruritus (itching) at the injection site.[4][5]

Peginterferon beta-1a was approved for medical use in the United States and in the European Union in 2014.[6][5]

Medical uses

In the United States, peginterferon beta-1a is indicated for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.[4]

In the European Union, peginterferon beta-1a is indicated for the treatment of relapsing remitting multiple sclerosis in adults.[5]

References

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