Pleuran

Chemical compound From Wikipedia, the free encyclopedia

Pleuran is an insoluble polysaccharide (β-(1,3/1,6)-D-glucan), isolated from Pleurotus ostreatus.[1]

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Pleuran
Identifiers
ChemSpider
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Properties
(C6H10O5)x
Molar mass Variable
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Pleuran belongs to a group of glucose polymers commonly called beta-glucans demonstrating biological response modifier properties. These immunomodulating properties render the host more resistant to infections and neoplasms.[2]

In a study published in December 2010, pleuran demonstrated to have a protective effect against exercise-induced suppression of immune cell activity (NK cells) in subjects taking 100 mg per day.[3]

In another study published in 2011, pleuran reduced the incidence of upper respiratory tract infections and increased the number of circulating NK cells.[4]

Pleuran is also being studied as a potential immunologic adjuvant.[5]

References

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