Pokémon Mystery Dungeon: Rescue Team DX

Similarly to the rest of the Pokémon Mystery Dungeon series, the game takes place in a world inhabited entirely by talking Pokémons. Some are townsfolk living in society, while others live in dungeons in the wild. The player awakes with amnesia, only remembering they were a human before. This is shocking to other Pokémons, as while they are aware of the existence of a human world, it is supposed to be separate from theirs. The first Pokémon the player meets quickly becomes their friend, and partners with them to create a rescue team, whose goal is to bring assistance to Pokémons in distress in the many dungeons of the world. The need for rescue teams is particularly acute, as the world is facing natural disasters of increasing frequency and intensity.

After starting small, the team soon begins to accomplish rescue missions in earnest. They meet other teams, including a top team led by Alakazam, and another one led by Gengar, with which a rivalry quickly forms. The team also learns of a legend about a human cursed for 1000 years by Ninetales for grabbing one of its tails, and how they let their Gardevoir be cursed instead. Ninetales then prophesied the human would be reborn as a Pokémon, upsetting the natural balance of the world. At around the same time, a Gardevoir starts appearing in the player's dreams. Soon after, the team journeys to fortune-teller Xatu, hoping to get some clarity. Xatu quickly realizes the player was once a human, and while they can tell their transformation is connected to the natural disasters, they are not definitive about the nature of this link. After eavesdropping on the conversation, Gengar proceeds to convince the townsfolk that the player is the human of the legend, and that killing them would return the world to normal. With the player's partner refusing to abandon them, the team is given one night to leave town before other teams start hunting them down. As they are being closely pursued, the team has to go through increasingly remote and difficult dungeons, while witnessing worsening disasters. During the journey they meet Absol, who seeks to find the true cause of the natural disasters and decides to join them. The team is eventually cornered by Alakazam and his team, but is rescued at the last moment by Ninetales, who reveals that the player is not the human of the legend and that their connection to it is a coincidence. However, Ninetales warns the disasters have awakened Groudon, putting the world in great danger.

While the team comes back to town to clear their name, Alakazam's team leaves to try and stop Groudon. After a few days have passed and Alakazam does not return, the town assembles a special team to go rescue them; however, this team is also defeated. Among growing defeatism, the player's team then volunteers to go defeat Groudon. The dungeon faced is more challenging than previous ones, but the team eventually manages to beat Groudon and rescue Alakazam with his team. Celebration in town is short-lived however, as Xatu urgently warns that a meteor, revealed to be the actual cause of the disasters, is approaching and threatens to destroy the world. The only way to stop it is to ask the sky guardian Rayquaza to destroy it. The night before the trip, Gardevoir appears in the player's dreams again. With Gengar listening through his Dream Eater move, she tells of how she still likes the human from the legend that abandoned her, despite his selfishness. At this, Gengar runs away crying. She then tells the player about their purpose in this world, which is to save it from the meteor, and how they agreed to lose their human memories in the process. The next day, Xatu, Alakazam, and Gengar create a Teleport Gem, letting the player’s team go to the sky. After going through its difficult dungeon and defeating Rayquaza, the latter agrees to destroy the meteor. The team reawakens on the ground, surrounded by the town, where they find that the world is safe once again. However, the player must return to being a human and leave the Pokémon world behind. After the credits roll, the player wishes hard to return, and reappears at the rescue team base in Pokémon form, to much shock from everybody else.