Polysaccharide-K

Protein-bound polysaccharide From Wikipedia, the free encyclopedia

Polysaccharide-K (Krestin, PSK) is a protein-bound polysaccharide isolated from the mycelium[1][2] of Trametes versicolor.

Trametes versicolor, the mushroom from which PSK was isolated.

Although PSK is approved in Japan as an adjuvant therapy in cancer treatment,[3] it is not approved in the United States for treatment of cancer or any clinical condition.[4]

Research

There is little evidence that turkey tail mushroom extracts or PSK are useful for treating cancer or any medical condition.[4]

Polysaccharide-K, an extract of T. versicolor, is approved in Japan as an adjuvant therapy in cancer treatment.[3]

Chemistry

PSK is a protein polysaccharide consisting of a beta-glucan β-1,4 main chain with β-1,3 and β-1,6 side chains. The approximate molecular weight of PSK is 100,000 Da, and the protein component is reported at the β-1,6 side chain.[5] PSK is isolated from the "CM-101" strain of Trametes versicolor. The analogous compound PSP, is derived from the "COV-1" strain of Trametes versicolor.[6]

See also

References

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