Her work is multidisciplinary which includes painting, installation, sculpture and photography.[7] She has exhibited in India and internationally in various museums/institutes including the Ullens Center for Contemporary Art, Beijing, China (2012), Zacheta National Gallery of Art, Warsaw, Poland (2011), Contemporary Art Center, Vilnius, Lithuania (2011), MAXXI National Museum of XXI Century, Rome (2011), Lyon Museum of Contemporary Art, Paris, France (2011), HEART Herning Museum of Contemporary Art, Denmark (2010), Asturp Fearnley Museum of Modern Art, Oslo, Norway (2009), Essl Museum of Contemporary Art, Austria (2010), KHOJ International Artists' Workshop, New Delhi (2009), KHOJ International Artists' Workshop, Mumbai (2009), National Gallery of Art, Mumbai (2002).[1]
Solo Exhibitions put up by her include "When the wind blows", Project 88, Mumbai (2016), "kitchen debate", Kunstlerhaus Bethanien, Berlin (2014), Time Lapse, The Guild, Mumbai (2012), Local time, Experimenter, Kolkata (2012) Porous Walls, The Guild Art Gallery, Mumbai, 2008; Membranes and Margins, Em Gallery, Seoul (2008); Walls in between, The Guild Art Gallery, Mumbai (2006).[1]
Potnis has received major awards for her work which include the Sanskriti Award for Art (2010), the Inlaks Fine Art Award (2003–04), and the Young Artist Fellowship, from the National Department of Culture (2002–03).[1]