Gupte worked for The New York Times for fifteen years. By 1975, as a local staff reporter, he was covering news for Suffolk County on Long Island; later, he was an international correspondent in Africa, the Middle East, and Asia. He then moved to Newsweek International and wrote as one of its global affairs columnists for eighteen years.[8] Over the years, Gupte has contributed columns to many other news venues, too, such as Forbes, Asian Finance, The Atlantic Monthly, Reader's Digest, People, The Cricketer (London), The Hindu (Chennai), and The Straits Times Singapore.
Gupte was also a columnist and business editor of The New York Sun and The Daily Star (Beirut).[9] In the late 1980s and early 1990s, he produced documentary films for PBS, Discovery Channel, and other outlets. Several of these documentaries profiled countries, for example, Belize, Malaysia, and Nepal. His documentaries also covered topics ranging from world banking to working women. He published op-eds in venues ranging from The Wall Street Journal and The Philadelphia Inquirer to the International Herald Tribune and The Los Angeles Times. He appeared on television as a guest commentator for CNN, Fox News, PBS, ABC and NBC, and on radio for BBC and NPR. He hosted a radio interview show on for PBS in New York. Gupte also became Editor-in-Chief of Al Arabiya International Network's English-language website, and created the site's Web TV.[8]
In 1991, he founded The Earth Times, a newspaper that appeared once every two weeks and that focused on environmental affairs, economic development, and issues relating to population and family planning. The Earth News appeared until 2003. In 1999, he launched an associated not-for-profit book division called Earth Times Books. The first book to appear in its series, an anthology called All of Us: Births and a Better Life: Population, Development and Environment in a Globalized World, included a contribution from Bill Clinton.[10] In 2012, Gupte published an obituary and tribute to his former boss, New York Times publisher Arthur Ochs Sulzberger, noting that Sulzberger was the first donor to The Earth Times when Gupte started it.[11]
From 2007 to 2011, Gupte was senior media advisor to His Highness Sheikh Mohammed bin Rashid Al Maktoum, Vice President and Prime Minister of the United Arab Emirates, and Ruler of Dubai.[8] In this position, Gupte helped Sheikh Maktoum to write his memoirs and English-language articles for the press.[12] Gupte served as a media advisor to organizations including the United Nations and World Bank, and moderated or featured in panels at the Davos conference.[8]
Gupte is an elected life member of the Council on Foreign Relations in New York.[8]
His books include Mother India: A Political Biography of Indira Gandhi (1992, 2009); The Crowded Earth: People and the Politics of Population (1984); and Global Emirates: An Anthology of Tolerance and Enterprise (2009).