Prinaberel

Prinaberel
Clinical data
ATC code	None;
Identifiers
	IUPAC name (4Z)-2-Fluoro-4-(5-hydroxy-7-vinyl-1,3-benzoxazol-2(3H)-ylidene)-2,5-cyclohexadien-1-one;
CAS Number	524684-52-4;
PubChem CID	5326893;
ChemSpider	4484184;
UNII	A9C8MNF7CA;
CompTox Dashboard (EPA)	DTXSID301030354 ;
ECHA InfoCard	100.222.969
Chemical and physical data
Formula	C15H10FNO3
Molar mass	271.247 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C3\C=C/C(=C2/Oc1c(cc(O)cc1N2)\C=C)/C=C3/F;
	InChI InChI=1S/C15H10FNO3/c1-2-8-5-10(18)7-12-14(8)20-15(17-12)9-3-4-13(19)11(16)6-9/h2-7,17-18H,1H2/b15-9-; Key:FCXYSEXZEGPLGG-DHDCSXOGSA-N;

Prinaberel (INN, USAN) (developmental code names ERB-041, WAY-202041) is a synthetic, nonsteroidal, and highly selective agonist of the ERβ subtype of the estrogen receptor.^[1] It is used in scientific research to elucidate the role of the ERβ receptor.^[2] Studies have indicated that selective ERβ agonists like prinaberel could be useful in the clinical treatment of a variety of medical conditions including inflammatory bowel disease, rheumatoid arthritis, endometriosis, and sepsis.^[3] Accordingly, prinaberel either was or still is under investigation by Wyeth for the treatment of some of these conditions.^[4]

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