Propargylamine

Propargylamine is an organic compound with the formula HC≡CCH₂NH₂. It is a colorless, odorless liquid that is used as a precursor to other compounds.^[1] Propargyl amines are produced by reactions of amines with propargyl halides.

Quick facts Names, Identifiers ...

Propargylamine

Names
Other names 2-Propyn-1-amine prop-2-yn-1-amine
Identifiers
CAS Number	2450-71-7
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL3263480
ChemSpider	208829
ECHA InfoCard	100.017.740
EC Number	219-513-8
PubChem CID	239041
CompTox Dashboard (EPA)	DTXSID30862951
InChI InChI=1S/C3H5N/c1-2-3-4/h1H,3-4H2 Key: JKANAVGODYYCQF-UHFFFAOYSA-N
SMILES C#CCN
Properties
Chemical formula	C3H5N
Molar mass	55.080 g·mol−1
Appearance	colorless liquid
Density	0.867 g/cm3
Boiling point	83 °C (181 °F; 356 K)
Refractive index (nD)	1.449
Hazards
GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H225, H302, H310, H314
Precautionary statements	P210, P233, P240, P241, P242, P243, P260, P262, P264, P264+P265, P270, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P321, P330, P361+P364, P363, P370+P378, P403+P235, P405, P501
Flash point	6 °C (43 °F; 279 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

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The behavior of propargyl amine is illustrated by its acylation benzoyl chloride to the amide. A Sonogashira coupling of the terminal alkyne end with another equivalent of benzoylchloride gives the dicarbonyl, a precursor to an oxazole.^[2]