Propylpyrazoletriol

Chemical compound From Wikipedia, the free encyclopedia

Propylpyrazoletriol (PPT) is a synthetic, nonsteroidal agonist of ERα with 400-fold selectivity over ERβ[1] that is used widely in scientific research to study the function of ERα.[2][3][4] Though originally thought to be highly selective for ERα, PPT has subsequently been found to also act as an agonist of the GPER (GPR30).[5]

CAS Number
PubChem CID
ChemSpider
UNII
Quick facts Identifiers, CAS Number ...
Propylpyrazoletriol
Identifiers
  • 4-[2,3-bis(4-hydroxyphenyl)-4-propyl-1H-pyrazol-5-ylidene]cyclohexa-2,5-dien-1-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC24H22N2O3
Molar mass386.451 g·mol−1
3D model (JSmol)
  • CCCC1=C(N(NC1=C2C=CC(=O)C=C2)C3=CC=C(C=C3)O)C4=CC=C(C=C4)O
  • InChI=1S/C24H22N2O3/c1-2-3-22-23(16-4-10-19(27)11-5-16)25-26(18-8-14-21(29)15-9-18)24(22)17-6-12-20(28)13-7-17/h4-15,25,28-29H,2-3H2,1H3
  • Key:UOSWGERPQQOSHS-UHFFFAOYSA-N
Close

See also

References

Related Articles

Wikiwand AI