Protein BEX1

BEX1
Identifiers
Aliases	BEX1, BEX2, HBEX2, HGR74-h, brain expressed X-linked 1
External IDs	OMIM: 300690; MGI: 1338017; HomoloGene: 135613; GeneCards: BEX1; OMA:BEX1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	103,064,171 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	134,968,985 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; middle temporal gyrus; ; orbitofrontal cortex; ; primary visual cortex; ; dorsolateral prefrontal cortex; ; superior frontal gyrus; ; Brodmann area 9; ; prefrontal cortex; ; pituitary gland;
	Top expressed in
	arcuate nucleus; ; ventromedial nucleus; ; paraventricular nucleus of hypothalamus; ; temporal lobe; ; amygdala; ; dorsomedial hypothalamic nucleus; ; lateral septal nucleus; ; anterior amygdaloid area; ; lateral hypothalamus; ; median eminence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; nucleus; transcription regulator complex;
Biological process	multicellular organism development; cell differentiation; positive regulation of DNA-binding transcription factor activity; nervous system development; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	55859
	12069
	ENSG00000133169
	ENSMUSG00000042750
	Q9HBH7
	Q9WTZ8
	NM_018476
	NM_009749
	NP_060946
	NP_033879
	Wikidata
View/Edit Human	View/Edit Mouse

Protein BEX1 also known as brain-expressed X-linked protein 1 is a protein that in humans is encoded by the BEX1 gene.^[5] BEX1 is a part of the BEX gene family well conserved in mammals. It is expressed in a wide range of tissues.^[6] BEX proteins have connections to cancer and their direct functions are not fully understood. BEX1 is suggested to act as a tumor suppressant in certain situations.^[6]