Proton-coupled amino acid transporter 1

Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene.^[5][6][7]

AliasesSLC36A1, Dct1, LYAAT1, PAT1, TRAMD3, solute carrier family 36 member 1

External IDsOMIM: 606561; MGI: 2445299; GeneCards: SLC36A1

Chr.Chromosome 5 (human)^[1]

End151,492,379 bp^[1]

Quick facts SLC36A1, Identifiers ...

SLC36A1
Identifiers
Aliases	SLC36A1, Dct1, LYAAT1, PAT1, TRAMD3, solute carrier family 36 member 1
External IDs	OMIM: 606561; MGI: 2445299; GeneCards: SLC36A1
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q33.1 Start 151,437,046 bp[1] End 151,492,379 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B1.3 Start 55,095,176 bp[2] End 55,127,156 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in jejunal mucosa duodenum right hemisphere of cerebellum mucosa of ileum trabecular bone trigeminal ganglion mucosa of colon rectum tendon of biceps brachii mucosa of sigmoid colon Top expressed in superior cervical ganglion spinal ganglia lumbar spinal ganglion visual cortex left colon jejunum stroma of bone marrow yolk sac primary visual cortex islet of Langerhans More reference expression data BioGPS More reference expression data
Gene ontology Molecular function amino acid:proton symporter activity L-proline transmembrane transporter activity neutral amino acid transmembrane transporter activity proton transmembrane transporter activity L-alanine transmembrane transporter activity glycine transmembrane transporter activity symporter activity amino acid transmembrane transporter activity Cellular component integral component of membrane membrane plasma membrane lysosomal membrane endoplasmic reticulum lysosome Biological process L-alanine transport proton transmembrane transport proline transmembrane transport ion transport proline transport amino acid transport glycine transport neutral amino acid transport transmembrane transport amino acid transmembrane transport transport Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 206358 215335 Ensembl ENSG00000123643 ENSMUSG00000020261 UniProt Q7Z2H8 Q8K4D3 RefSeq (mRNA) NM_001308150 NM_001308151 NM_078483 NM_001349740 NM_153139 RefSeq (protein) NP_001295079 NP_001295080 NP_510968 NP_001336669 NP_694779 Location (UCSC) Chr 5: 151.44 – 151.49 Mb Chr 11: 55.1 – 55.13 Mb PubMed search [3] [4]
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This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.^[7]