Protoporphyrinogen IX dehydrogenase (menaquinone)
From Wikipedia, the free encyclopedia
Protoporphyrinogen IX dehydrogenase (menaquinone) (EC 1.3.5.3, HemG) is an enzyme with systematic name protoporphyrinogen IX:menaquinone oxidoreductase.[1] This enzyme catalyses the following chemical reaction
| Protoporphyrinogen IX dehydrogenase (menaquinone) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.3.5.3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme uses three equivalents of menaquinone per molecule of protoporphyrinogen IX to provide the oxidant. It enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments.[2][3]
