Pseudomonas sRNA P16
RNA family
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Pseudomonas sRNA P16 is a ncRNA that was predicted using bioinformatic tools in the genome of the opportunistic pathogen Pseudomonas aeruginosa and its expression verified by northern blot analysis.[1] P16 sRNA appears to be conserved across several Pseudomonas species and is consistently located downstream of a predicted TatD deoxyribonuclease gene. P16 has a predicted Rho independent terminator at the 3′ end but the function of P16 is unknown.[1]
| Pseudomonas sRNA P16 | |
|---|---|
Predicted secondary structure and sequence conservation of P16 | |
| Identifiers | |
| Symbol | P16 |
| Rfam | RF00628 |
| Other data | |
| RNA type | Gene |
| Domain | Bacteria |
| SO | SO:0000655 |
| PDB structures | PDBe |
It has been shown that this sRNA is transcribed from an RpoS-dependent promoter under positive, probably indirect GacA control in two Pseudomonas species. It was renamed RgsA (for regulation by GacA and stress).[2] RpoS mRNA expression is repressed by RgsA during the exponential phase. The Hfq RNA chaperone is required for the repression.[3]
