PurD RNA motif
From Wikipedia, the free encyclopedia
| purD RNA motif | |
|---|---|
 Predicted secondary structure and sequence conservation of purD | |
| Identifiers | |
| Symbol | purD |
| Rfam | RF01069 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Bacteria |
| SO | SO:0005836 |
| PDB structures | PDBe |
The purD RNA motif is a conserved RNA structure found in Campylobacterota, such as the genera Helicobacter and Campylobacter.[1] The RNA is consistently found in the apparent 5' UTR of purD genes. purD genes encode the enzyme Phosphoribosylamine-glycine ligase, which catalyzes an early step in de novo purine synthesis. Although a possible cis-regulatory role was proposed for this motif, experimental results indicate that it overlaps the 6S RNA of the relevant species,[2] and that the second hairpin of the motif might not be biological.
