Pyrogallol 1,2-oxygenase

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Pyrogallol 1,2-oxygenase (EC 1.13.11.35) is an enzyme that catalyzes the chemical reaction

 
O2
 
Rightward reaction arrow with minor substrate(s) from top left
 
 
 
2D representation of the chemical structure of Q27104228.
(Z)-5-oxohex-2-enedioic acid

The two substrates of this enzyme are pyrogallol and oxygen. Its product is (Z)-5-oxohex-2-enedioic acid. The enzyme was first isolated from Azotobacter vinelandii.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is 1,2,3-trihydroxybenzene:oxygen 1,2-oxidoreductase (decyclizing). This enzyme is also called pyrogallol 1,2-dioxygenase.

References

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