Pyrogallol hydroxytransferase
From Wikipedia, the free encyclopedia
Pyrogallol hydroxytransferase (EC 5.4.4.9) is an enzyme that catalyzes a chemical reaction that converts pyrogallol to phloroglucinol by formation of the intermediate 1,2,3,5-tetrahydroxybenzene.[1]
| Pyrogallol hydroxytransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.4.4.9 | ||||||||
| CAS no. | 125978-84-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme isolated from the bacterium Pelobacter acidigallici contains molybdenum but the hydroxyl group which is initially added to pyrogallol does not come from water. Instead, some sulfoxides and aromatic N-oxides can provide these groups.[2][3]
Nomenclature
This enzyme belongs to the family of oxidoreductases. The systematic name of this enzyme class is 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase. Other names in common use include 1,2,3,5-tetrahydroxybenzene hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase, 1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase), pyrogallol hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase.[4]
