Quinestradol

Quinestradol (INNTooltip International Nonproprietary Name, BANTooltip British Approved Name) (brand names Colpovis, Colpovister, Pentovis), also known as quinestradiol or quinestriol, as well as estriol 3-cyclopentyl ether (E3CPE), is a synthetic estrogen and estrogen ether which is no longer marketed.^[1][2][3][4] It is the 3-cyclopentyl ether of estriol.^[1] The medication has been studied in the treatment of stress incontinence in elderly women, with effectiveness observed.^[3][4]

Trade namesColpovis, Colpovister, Pentovis

Other namesQuinestradiol; Quinestriol; Estriol 3-cyclopentyl ether; E3CPE

Routes of
administrationBy mouth

Drug classEstrogen; Estrogen ether

Quick facts Clinical data, Trade names ...

Quinestradol

Clinical data
Trade names	Colpovis, Colpovister, Pentovis
Other names	Quinestradiol; Quinestriol; Estriol 3-cyclopentyl ether; E3CPE
Routes of administration	By mouth
Drug class	Estrogen; Estrogen ether
ATC code	None
Identifiers
IUPAC name (8R,9S,13S,14S,16R,17R)-3-cyclopentyloxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-16,17-diol
CAS Number	1169-79-5 Y
PubChem CID	14431
ChemSpider	16735993
UNII	422L8173W8
CompTox Dashboard (EPA)	DTXSID30878638
ECHA InfoCard	100.013.294
Chemical and physical data
Formula	C23H32O3
Molar mass	356.506 g·mol−1
3D model (JSmol)	Interactive image
SMILES CC12CCC3C(C1CC(C2O)O)CCC4=C3C=CC(=C4)OC5CCCC5
InChI InChI=1S/C23H32O3/c1-23-11-10-18-17-9-7-16(26-15-4-2-3-5-15)12-14(17)6-8-19(18)20(23)13-21(24)22(23)25/h7,9,12,15,18-22,24-25H,2-6,8,10-11,13H2,1H3/t18-,19-,20+,21-,22+,23+/m1/s1 Key:ODYKCPYPRCJXLY-PZORDLPLSA-N

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