RNF5

Protein-coding gene in the species Homo sapiens From Wikipedia, the free encyclopedia

E3 ubiquitin-protein ligase RNF5 is an enzyme that in humans is encoded by the RNF5 gene.[5][6]

AliasesRNF5, RING5, RMA1, ring finger protein 5
End32,180,793 bp[1]
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RNF5
Identifiers
AliasesRNF5, RING5, RMA1, ring finger protein 5
External IDsOMIM: 602677; MGI: 1860076; HomoloGene: 56004; GeneCards: RNF5; OMA:RNF5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006913

NM_019403

RefSeq (protein)

NP_008844

NP_062276

Location (UCSC)Chr 6: 32.18 – 32.18 MbChr 17: 34.82 – 34.82 Mb
PubMed search[3][4]
Wikidata
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Function

The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.[6]

References

Further reading

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