RNF5
Protein-coding gene in the species Homo sapiens
From Wikipedia, the free encyclopedia
E3 ubiquitin-protein ligase RNF5 is an enzyme that in humans is encoded by the RNF5 gene.[5][6]
External IDsOMIM: 602677; MGI: 1860076; HomoloGene: 56004; GeneCards: RNF5; OMA:RNF5 - orthologs
Function
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.[6]