RPS6KA4

RPS6KA4
Identifiers
Aliases	RPS6KA4, MSK2, RSK-B, S6K-alpha-4, ribosomal protein S6 kinase A4
External IDs	OMIM: 603606; MGI: 1930076; HomoloGene: 69288; GeneCards: RPS6KA4; OMA:RPS6KA4 - orthologs
Enzyme activity
Gene location (Human)
Chr.	Chromosome 11 (human)
End	64,372,215 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	6,818,004 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; granulocyte; ; monocyte; ; right frontal lobe; ; apex of heart; ; right coronary artery; ; mucosa of transverse colon; ; cingulate gyrus; ; prefrontal cortex; ; anterior cingulate cortex;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; metal ion binding; kinase activity; protein serine/threonine kinase activity; ribosomal protein S6 kinase activity; protein binding; ATP binding; magnesium ion binding;
Cellular component	nucleoplasm; nucleus; cytoplasm; cytosol;
Biological process	intracellular signal transduction; regulation of transcription, DNA-templated; phosphorylation; positive regulation of histone acetylation; interleukin-1-mediated signaling pathway; protein phosphorylation; positive regulation of CREB transcription factor activity; positive regulation of NF-kappaB transcription factor activity; inflammatory response; negative regulation of cytokine production; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	8986
	56613
	ENSG00000162302
	ENSMUSG00000118668
	O75676
	Q9Z2B9
	NM_001006944; NM_001300802; NM_003942; NM_001318361
	NM_019924
	NP_001006945; NP_001287731; NP_001305290; NP_003933
	NP_064308
	Wikidata
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