Ralph married Margaret Gascoigne, daughter of Sir William Gascoigne and Margaret Percy, daughter of Henry Percy, 3rd Earl of Northumberland. Ralph and Margaret had at least six children:
- Robert Ogle, 4th Baron Ogle (1490–1530) who married Anne Lumley
- Sir William Ogle
- John Ogle
- Anne Ogle, married Sir John Delaval, Sheriff of Northumberland (died 3 January 1572), & married Humphrey Lisle
- Dorothy Ogle who married Sir Thomas Forster. Second marriage to Thomas Grey of Horton.
- Margery Ogle who married George Harbottle
He died on 16 January 1512 in Morpeth, Northumberland and there is a tomb to him and Margaret, who is also said to have died in 1512, in St Andrew's church, Bothal, Northumberland.