RDH11

Retinol dehydrogenase 11 is an enzyme that in humans is encoded by the RDH11 gene.^[4][5][6][7]

AliasesRDH11, ARSDR1, CGI82, HCBP12, MDT1, PSDR1, RALR1, SCALD, SDR7C1, RDJCSS, retinol dehydrogenase 11 (all-trans/9-cis/11-cis), retinol dehydrogenase 11

External IDsOMIM: 607849; MGI: 102581; GeneCards: RDH11

Chr.Chromosome 14 (human)^[1]

End67,695,793 bp^[1]

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RDH11
Identifiers
Aliases	RDH11, ARSDR1, CGI82, HCBP12, MDT1, PSDR1, RALR1, SCALD, SDR7C1, RDJCSS, retinol dehydrogenase 11 (all-trans/9-cis/11-cis), retinol dehydrogenase 11
External IDs	OMIM: 607849; MGI: 102581; GeneCards: RDH11
Enzyme activity EC # BRENDA ExPASy KEGG MetaCyc 1.1.1.300 ↗ ↗ ↗ ↗
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q24.1 Start 67,676,800 bp[1] End 67,695,793 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in retinal pigment epithelium islet of Langerhans Brodmann area 23 kidney tubule pars compacta tibia skin of thigh pars reticulata corpus epididymis vulva n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor NADP-retinol dehydrogenase activity NAD-retinol dehydrogenase activity protein binding aldehyde dehydrogenase (NADP+) activity Cellular component integral component of membrane intracellular anatomical structure endoplasmic reticulum membrane membrane endoplasmic reticulum photoreceptor inner segment Biological process retinoid metabolic process retinol metabolic process retinal metabolic process adaptation of rhodopsin mediated signaling visual perception cellular detoxification of aldehyde Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 51109 17252 Ensembl ENSG00000072042 n/a UniProt Q8TC12 Q9QYF1 RefSeq (mRNA) NM_016026 NM_001252650 NM_021557 NM_001362269 NM_001362270 RefSeq (protein) NP_001239579 NP_057110 NP_067532 NP_001349198 NP_001349199 Location (UCSC) Chr 14: 67.68 – 67.7 Mb n/a PubMed search [2] [3]
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RHD11, a member of the short-chain dehydrogenase/reductase (SDR) superfamily of oxidoreductases, is expressed at high levels in prostate epithelium, and its expression is regulated by androgens.[supplied by OMIM]^[7]