Born in Rome, Rossi began his professional career in 1984, starring in a Fiat commercial directed by Paolo Bianchini.[1] The same year, he made his film debut in Castellano & Pipolo's College.[1][2] At the end of the decade, he became first known playing Mazzocchi in the Italia 1 comedy series I ragazzi della 3ª C.[1][2][3]
In 1992, Rossi worked as a comedian on the television program Non è la Rai,[1] and one year later, he made his debut as television presenter in the Canale 5 children's show A tutto Disney.[2] He then worked in a large number of television programs, notably Forum, Buona domenica, Carràmba che fortuna, Quelli che... il calcio.[1][2] In 2004, he co-hosted with Paola Cortellesi Nessundorma.[2][4] Between 2010 and 2017, he was a juror in the La7competitive cooking reality show Cuochi e fiamme, appearing in about 350 episodes.[2][3]
In 2015, Rossi made his directorial debut with La prima volta (di mia figlia).[5][6] Starting from 2017, Rossi is the presenter of I miei vinili, later renamed I vinili di..., a talk show first broadcast on Sky and later on RAI.[7][8][9]