Ro 04-6790

Ro 04-6790
Clinical data
ATC code	none;
Identifiers
	IUPAC name 4-amino-N-[2,6-bis(methylamino)-4-pyrimidinyl]-benzenesulfonamide;
CAS Number	202466-68-0;
PubChem CID	5312145;
IUPHAR/BPS	274;
ChemSpider	4471575;
UNII	CU78RAR5ZH;
ChEMBL	ChEMBL433461;
CompTox Dashboard (EPA)	DTXSID701017998 ;
Chemical and physical data
Formula	C12H16N6O2S
Molar mass	308.36 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Nc2ccc(cc2)S(=O)(=O)Nc1cc(NC)nc(NC)n1;
	InChI InChI=1S/C12H16N6O2S/c1-14-10-7-11(17-12(15-2)16-10)18-21(19,20)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H3,14,15,16,17,18); Key:JELFWSXQTXRMAJ-UHFFFAOYSA-N;
	(verify)

Ro 04-6790 is a drug, developed by Hoffmann–La Roche, which has applications in scientific research. It acts as a potent and selective receptor antagonist for the 5-HT₆ serotonin receptor subtype, with little or no affinity at other receptors. In common with other drugs of this class,^[1] Ro 04-6790 has nootropic effects in animals,^[2] and reduces the amnesia produced by memory-impairing drugs such as dizocilpine^[3] and scopolamine.^[4]

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