Rosemary Carpenter
British plant geneticist
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Rosemary Carpenter is a British plant geneticist known for her work on members of the genus Antirrhinum, commonly known as a snapdragon, for which she and Enrico Coen were awarded the 2004 Darwin Medal by the Royal Society.[1]
Rosemary Carpenter | |
|---|---|
| Alma mater | University of East Anglia |
| Scientific career | |
| Institutions | John Innes Centre |
| Thesis | Studies on genetic instability in Antirrhinum majus (1998) |
Career
Starting in the 1960, Carpenter worked with Brian Harrison at the John Innes Centre on unstable mutants of the snapdragon Antirrhinum.[2] After meeting Carpenter during an interview at the John Innes Centre in 1983, Enrico Coen joined the center and they began a long collaboration with him using snapdragons as a model system to understand jumping genes and evolution.[3][2] They applied a combination of molecular, genetic and morphological approaches to snapdragons with the goal of elucidating patterns in flower development[4] using the hundreds of Antirrhihum mutants established by Carpenter.[5] Carpenter retired in 2003.[6]
Research
Carpenter is a plant geneticist known for her research on the population genetics of the snapdragon, Antirrhihum.[7][2] Working with Brian Harrison in the 1970s, she defined genetic instabilities in Antirrhinum and the role of temperature in controlling the rate of instability of specific genes[8][9] and transposable elements that occur in both maize and snapdragons.[10] This was the first time a link between genetic instability and Antirrhihum was formalized, a milestone in research using snapdragons.[11] The instability of genes in snapdragons begin Carpenter's collaboration with Enrico Coen, where they first worked on transposons and the effect of temperature on the excision of specific genes[12] and how the transposable elements cause variability in gene expression.[13][14] Carpenter, Coen, and their students isolated the genes controlling floral development.[15][16][17] These genetic investigations allowed them to define the patterns of color,[18][19] shape,[20][21][22] and floral asymmetry[23][24] in snapdragons and other plants. Carpenter's research on snapdragons includes investigations of how snapdragons select their colors using small RNA,[25] which alter the selection of colors in the snapdragons.[26]
Selected publications
- Carpenter, R; Coen, E S (1 September 1990). "Floral homeotic mutations produced by transposon-mutagenesis in Antirrhinum majus". Genes & Development. 4 (9): 1483–1493. doi:10.1101/gad.4.9.1483. ISSN 0890-9369. PMID 1979295.
- Coen, Enrico S.; Romero, JoséM.; Doyle, Sandra; Elliott, Robert; Murphy, George; Carpenter, Rosemary (1990). "floricaula: A homeotic gene required for flower development in antirrhinum majus". Cell. 63 (6): 1311–1322. doi:10.1016/0092-8674(90)90426-F. PMID 1702033. S2CID 46586130.
- Carpenter, R.; Coen, E.S. (1 January 1995). "Transposon induced chimeras show that floricaula, a meristem identity gene, acts non-autonomously between cell layers". Development. 121 (1): 19–26. doi:10.1242/dev.121.1.19. ISSN 0950-1991. PMID 7867500.
- Luo, Da; Carpenter, Rosemary; Vincent, Coral; Copsey, Lucy; Coen, Enrico (1996). "Origin of floral asymmetry in Antirrhinum". Nature. 383 (6603): 794–799. Bibcode:1996Natur.383..794L. doi:10.1038/383794a0. ISSN 0028-0836. PMID 8893002. S2CID 2188470.
- Bradley, Desmond; Carpenter, Rosemary; Copsey, Lucy; Vincent, Coral; Rothstein, Steven; Coen, Enrico (February 1996). "Control of inflorescence architecture in Antirrhinum". Nature. 379 (6568): 791–797. Bibcode:1996Natur.379..791B. doi:10.1038/379791a0. PMID 8587601. S2CID 998958.