The song for the most part met with a positive reception, with Danitha J of The Source calling the collaboration between Lecrae and B.o.B "epic" and praising Lecrae for his positive message.[6] Writing for Jesus Freak Hideout, Kevin Hoskins thought "Lecrae and B.O.B. spit honest words laid over nice beats throughout the entire listen".[7] Christian Music Zine considered the song a highlight from the album,[8] and HipHopDX praising "Round of Applause", alongside the tracks "Misconception pt. 2" and "Was it Worth it", for offering topical and conceptual depth.[9] On June 4, 2013, Lecrae performed the single live on BET's 106 & Park.[10] On June 21, 2013, Pepsi included the extended version of the song in its list "Three Songs You Need to Hear Right Now", along with Justin Timberlake's "Don't Hold the Wall" and will.i.am's "Bang Bang".[2][11] "Round of Applause" charted at No. 45 on the Christian Songs chart.[12]
In contrast to this reception, Aubrey McKay of Wade-O Radio leveled criticism at the song, in particular the collaboration with B.o.B. McKay stated that in his opinion Lecrae and B.o.B "didn't mesh well together", and that "B.o.B.'s verse was sub-par".[13]