Rozalyn Anderson

In the Sinclair laboratory at Harvard Medical School, Anderson researched the regulation of the lifespan by calorie restriction in yeast, demonstrating that lifespan could be extended by genetic manipulation of the NAD⁺ salvage pathway,^[5][6] and that calorie restriction downregulates NAD⁺.^[7]

Anderson worked as part of the University of Wisconsin team that demonstrated that caloric restriction has a beneficial effect in rhesus monkeys, improves survival, and lowers the incidence of diseases including diabetes, cancer, and cardiovascular disease over the course of nearly three decades.^{[8][9][10][11]} She continues to study caloric restriction, focusing on primate skeletal muscle, white adipose tissue, inflammation, mitochondrial dysfunction, and metabolic regulators of cancer growth.^[3]

In a 2014 interview discussing the different results of the National Institute of Aging and University of Wisconsin rhesus monkey caloric restriction studies, Anderson points out that due to the experimental setup, both the control and experimental groups were calorie restricted to some degree, which explains why no significant improvement was found in the experimental group. She also points out that the two studies are more informative due to their differing designs than if they had been performed identically.^{[12] [13]}

In 2013, Anderson won the Nathan Shock New Investigator Award from the Gerontological Society of America.^[14][15]

From 2019-2021, Anderson served as the President of the American Aging Association.^[16]

Anderson is the co-editor-in-chief of The Journals of Gerontology Series A: Biological Sciences.^[17]

• YouTube lecture