RyeB RNA
Non-coding RNA
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The SdsR/RyeB RNA is a non-coding RNA that was identified in a large scale screen of E. coli.[1] The exact 5′ and 3′ ends of this RNA are uncertain. This RNA overlaps the SraC/RyeA RNA on the opposite strand suggesting that the two may act in a concerted manner. It is transcribed by general stress factor σs and is most highly expressed in stationary phase. SdsR/RyeB RNA interacts with Hfq.
| SdsR/RyeB RNA | |
|---|---|
Predicted secondary structure and sequence conservation of SdsR_RyeB | |
| Identifiers | |
| Symbol | SdsR_RyeB |
| Rfam | RF00111 |
| Other data | |
| RNA type | Gene; sRNA |
| Domain | Bacteria |
| SO | SO:0000655 |
| PDB structures | PDBe |
The homologous sRNA in S. enterica was shown to regulate synthesis of major porin OmpD.[2] A study using Salmonella identified 20 targets of this sRNA including transcriptional regulator, CRP, global DNA-binding factors, StpA and HupB, the antibiotic transporter protein, TolC, and the RtsA/B two-component system (TCS), and validated their post-transcriptional control by SdsR/RyeB RNA.[3]